UA cloudflare authentication

 

Intraindividual variability in sleep and comorbid medical and mental health conditions

Simple item page
dc.contributor.authorSlavish, Danica C.
dc.contributor.authorTaylor, Daniel J.
dc.contributor.authorLichstein, Kenneth L.
dc.contributor.otherUniversity of North Texas Denton
dc.contributor.otherUniversity of Alabama Tuscaloosa
dc.date.accessioned2023-09-28T22:03:52Z
dc.date.available2023-09-28T22:03:52Z
dc.date.issued2019
dc.description.abstractStudy Objectives: Intraindividual variability (IIV) in sleep may be a risk factor for disease above the influence of mean sleep. Associations between IIV in sleep and risk for a comprehensive set of common medical and mental health conditions have not been assessed in a representative sample. Methods: This study examined mean and IIV in total sleep time (TST), sleep quality (SQ), sleep efficiency (SE), and circadian midpoint (CM) in 771 adults recruited for an epidemiological study. Participants completed 14 days of sleep diaries to assess TST, SQ, SE, and CM, after which they reported on medical conditions and mental health symptoms. Data were analyzed using logistic regression, and models controlled for gender, body mass index, age, and race. Results: Lower mean TST, SQ, and SE were related to increased odds of having gastrointestinal problems, depression, and anxiety. IIV in TST was related to increased odds of having neurological, breathing, and gastrointestinal problems, as well as pain and depression; all results held controlling for mean sleep and adjusting for false discovery rate. IIV in SQ and SE was not associated with odds of having any medical or mental health conditions after adjusting for false discovery rate, nor was IIV in CM or mean CM. Conclusions: Confirming previous research, mean TST, SQ, and SE are related to risk for gastrointestinal problems, depression, and anxiety. IIV in TST may be a unique facet of disturbed sleep that is associated with increased risk for a diverse cluster of medical and mental health conditions.en_US
dc.format.mediumelectronic
dc.format.mimetypeapplication/pdf
dc.identifier.citationSlavish, D. C., Taylor, D. J., & Lichstein, K. L. (2019). Intraindividual variability in sleep and comorbid medical and mental health conditions. In Sleep (Vol. 42, Issue 6). Oxford University Press (OUP). https://doi.org/10.1093/sleep/zsz052
dc.identifier.doi10.1093/sleep/zsz052
dc.identifier.orcidhttps://orcid.org/0000-0002-1924-4895
dc.identifier.urihttps://ir.ua.edu/handle/123456789/12227
dc.languageEnglish
dc.language.isoen_US
dc.publisherOxford University Press
dc.subjectintraindividual variability
dc.subjectepidemiology
dc.subjectsleep diaries
dc.subjectmedical conditions
dc.subjectpublic health
dc.subjecttotal sleep time
dc.subjectPITUITARY-ADRENAL AXIS
dc.subjectC-REACTIVE PROTEIN
dc.subjectNIGHT-SHIFT WORK
dc.subjectCIRCADIAN MISALIGNMENT
dc.subjectHPA AXIS
dc.subjectCARDIOVASCULAR CONSEQUENCES
dc.subjectRISK
dc.subjectDEPRESSION
dc.subjectSTRESS
dc.subjectDURATION
dc.subjectClinical Neurology
dc.subjectNeurosciences
dc.titleIntraindividual variability in sleep and comorbid medical and mental health conditionsen_US
dc.typeArticle
dc.typetext

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
10.1093sleepzsz052.pdf
Size:
1.27 MB
Format:
Adobe Portable Document Format
Download

Collections

Research and Publications - Department of Health Science