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Body composition assessment in adults with down syndrome

dc.contributorRichardson, Mark T.
dc.contributorFedewa, Michael V.
dc.contributorStran, Margaret E.
dc.contributorConners, Frances A.
dc.contributor.advisorEsco, Michael R.
dc.contributor.authorRussell, Angela R.
dc.contributor.otherUniversity of Alabama Tuscaloosa
dc.date.accessioned2018-06-04T14:57:24Z
dc.date.available2018-06-04T14:57:24Z
dc.date.issued2017-12
dc.descriptionElectronic Thesis or Dissertationen_US
dc.description.abstractIndividuals with Down syndrome (DS) have a high prevalence of obesity and low bone mineral density (BMD), but body composition assessment needs additional study in DS. Three studies examined the agreement between body fat percentage (BF%) from air displacement plethysmography (ADP) and dual-energy x-ray absorptiometry (DXA), BF% from a four-compartment (4C) model and skinfolds (SF) and bioelectrical impedance analysis (BIA), and bone mineral content (BMC) from DXA and BIA. Sixty-six adults participated (33 DS, 33 control). In the first study, DXA provided higher BF% than ADP in both DS (t = 5.252, df = 32, p < .000) and controls (t = 7.714, df = 32, p < .000). In the second study, BF% from four BIA equations was not significantly different from 4CBF% in DS (p > .01), but these had a standard error of estimate (SEE) from 4.8 to 6.0 and wide limits of agreement (± 9.5% to ± 11.6%). Two BIA equations were not significantly different than 4CBF% in controls (p < .01), but these had SEE’s of 7.2 and 7.8 and wide limits of agreement (± 24.6% and ± 22.9%). Two SF equations were not significantly different from 4CBF% in DS (p < .007). Two of the SF equations were significantly different from 4CBF% in controls (p < .008). In the third study, BMC from DXA was significantly lower than BIA in DS (t = -5.237, df = 20, p < .000). DXA was significantly higher in controls (t = 3.110, df = 20, p = .006). There was no significant difference in DS males (t = -1.116, df = 7, p = .301) or control females (t = -7.978, df = 12, p = .000). DXA was significantly higher in control males (t = 5.641, df = 7, p = .001) and significantly lower in females with DS (t = -7.978, df = 12, p = .000). In conclusion, many methods of BF% assessment may be acceptable for adults with DS, but only appropriate equations should be selected. BIA should not currently be used to assess BMC in DS.en_US
dc.format.extent121 p.
dc.format.mediumelectronic
dc.format.mimetypeapplication/pdf
dc.identifier.otheru0015_0000001_0002843
dc.identifier.otherRussell_alatus_0004D_13354
dc.identifier.urihttp://ir.ua.edu/handle/123456789/3519
dc.languageEnglish
dc.language.isoen_US
dc.publisherUniversity of Alabama Libraries
dc.relation.hasversionborn digital
dc.relation.ispartofThe University of Alabama Electronic Theses and Dissertations
dc.relation.ispartofThe University of Alabama Libraries Digital Collections
dc.rightsAll rights reserved by the author unless otherwise indicated.en_US
dc.subjectKinesiology
dc.subjectPublic health
dc.subjectHealth sciences
dc.titleBody composition assessment in adults with down syndromeen_US
dc.typethesis
dc.typetext
etdms.degree.departmentUniversity of Alabama. Department of Kinesiology
etdms.degree.disciplineHuman Performance
etdms.degree.grantorThe University of Alabama
etdms.degree.leveldoctoral
etdms.degree.namePh.D.

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