The genomes of two key bumblebee species with primitive eusocial organization

dc.contributor.authorSadd, Ben M.
dc.contributor.authorBarribeau, Seth M.
dc.contributor.authorBloch, Guy
dc.contributor.authorde Graaf, Dirk C.
dc.contributor.authorDearden, Peter
dc.contributor.authorElsik, Christine G.
dc.contributor.authorGadau, Juergen
dc.contributor.authorGrimmelikhuijzen, Cornelis J. P.
dc.contributor.authorHasselmann, Martin
dc.contributor.authorLozier, Jeffrey D.
dc.contributor.authorRobertson, Hugh M.
dc.contributor.authorSmagghe, Guy
dc.contributor.authorStolle, Eckart
dc.contributor.authorVan Vaerenbergh, Matthias
dc.contributor.authorWaterhouse, Robert M.
dc.contributor.authorBornberg-Bauer, Erich
dc.contributor.authorKlasberg, Steffen
dc.contributor.authorBennett, Anna K.
dc.contributor.authorCamara, Francisco
dc.contributor.authorGuigo, Roderic
dc.contributor.authorHoff, Katharina
dc.contributor.authorMariotti, Marco
dc.contributor.authorMunoz-Torres, Monica
dc.contributor.authorMurphy, Terence
dc.contributor.authorSantesmasses, Didac
dc.contributor.authorAmdam, Gro V.
dc.contributor.authorBeckers, Matthew
dc.contributor.authorBeye, Martin
dc.contributor.authorBiewer, Matthias
dc.contributor.authorBitondi, Marcia M. G.
dc.contributor.authorBlaxter, Mark L.
dc.contributor.authorBourke, Andrew F. G.
dc.contributor.authorBrown, Mark J. F.
dc.contributor.authorBuechel, Severine D.
dc.contributor.authorCameron, Rossanah
dc.contributor.authorCappelle, Kaat
dc.contributor.authorCarolan, James C.
dc.contributor.authorChristiaens, Olivier
dc.contributor.authorCiborowski, Kate L.
dc.contributor.authorClarke, David F.
dc.contributor.authorColgan, Thomas J.
dc.contributor.authorCollins, David H.
dc.contributor.authorCridge, Andrew G.
dc.contributor.authorDalmay, Tamas
dc.contributor.authorDreier, Stephanie
dc.contributor.authordu Plessis, Louis
dc.contributor.authorDuncan, Elizabeth
dc.contributor.authorErler, Silvio
dc.contributor.authorEvans, Jay
dc.contributor.authorFalcon, Tiago
dc.contributor.authorFlores, Kevin
dc.contributor.authorFreitas, Flavia C. P.
dc.contributor.authorFuchikawa, Taro
dc.contributor.authorGempe, Tanja
dc.contributor.authorHartfelder, Klaus
dc.contributor.authorHauser, Frank
dc.contributor.authorHelbing, Sophie
dc.contributor.authorHumann, Fernanda C.
dc.contributor.authorIrvine, Frano
dc.contributor.authorJermiin, Lars S.
dc.contributor.authorJohnson, Claire E.
dc.contributor.authorJohnson, Reed M.
dc.contributor.authorJones, Andrew K.
dc.contributor.authorKadowaki, Tatsuhiko
dc.contributor.authorKidner, Jonathan H.
dc.contributor.authorKoch, Vasco
dc.contributor.authorKoehler, Arian
dc.contributor.authorKraus, F. Bernhard
dc.contributor.authorLattorff, H. Michael G.
dc.contributor.authorLeask, Megan
dc.contributor.authorLockett, Gabrielle A.
dc.contributor.authorMallon, Eamonn B.
dc.contributor.authorAntonio, David S. Marco
dc.contributor.authorMarxer, Monika
dc.contributor.authorMeeus, Ivan
dc.contributor.authorMoritz, Robin F. A.
dc.contributor.authorNair, Ajay
dc.contributor.authorNapflin, Kathrin
dc.contributor.authorNissen, Inga
dc.contributor.authorNiu, Jinzhi
dc.contributor.authorNunes, Francis M. F.
dc.contributor.authorOakeshott, John G.
dc.contributor.authorOsborne, Amy
dc.contributor.authorOtte, Marianne
dc.contributor.authorPinheiro, Daniel G.
dc.contributor.authorRossie, Nina
dc.contributor.authorRueppell, Olav
dc.contributor.authorSantos, Carolina G.
dc.contributor.authorSchmid-Hempel, Regula
dc.contributor.authorSchmitt, Bjoern D.
dc.contributor.authorSchulte, Christina
dc.contributor.authorSimoes, Zila L. P.
dc.contributor.authorSoares, Michelle P. M.
dc.contributor.authorSwevers, Luc
dc.contributor.authorWinnebeck, Eva C.
dc.contributor.authorWolschin, Florian
dc.contributor.authorYu, Na
dc.contributor.authorZdobnov, Evgeny M.
dc.contributor.authorAqrawi, Peshtewani K.
dc.contributor.authorBlankenburg, Kerstin P.
dc.contributor.authorCoyle, Marcus
dc.contributor.authorFrancisco, Liezl
dc.contributor.authorHernandez, Alvaro G.
dc.contributor.authorHolder, Michael
dc.contributor.authorHudson, Matthew E.
dc.contributor.authorJackson, LaRonda
dc.contributor.authorJayaseelan, Joy
dc.contributor.authorJoshi, Vandita
dc.contributor.authorKovar, Christie
dc.contributor.authorLee, Sandra L.
dc.contributor.authorMata, Robert
dc.contributor.authorMathew, Tittu
dc.contributor.authorNewsham, Irene F.
dc.contributor.authorNgo, Robin
dc.contributor.authorOkwuonu, Geoffrey
dc.contributor.authorPham, Christopher
dc.contributor.authorPu, Ling-Ling
dc.contributor.authorSaada, Nehad
dc.contributor.authorSantibanez, Jireh
dc.contributor.authorSimmons, DeNard
dc.contributor.authorThornton, Rebecca
dc.contributor.authorVenkat, Aarti
dc.contributor.authorWalden, Kimberly K. O.
dc.contributor.authorWu, Yuan-Qing
dc.contributor.authorDebyser, Griet
dc.contributor.authorDevreese, Bart
dc.contributor.authorAsher, Claire
dc.contributor.authorBlommaert, Julie
dc.contributor.authorChipman, Ariel D.
dc.contributor.authorChittka, Lars
dc.contributor.authorFouks, Bertrand
dc.contributor.authorLiu, Jisheng
dc.contributor.authorO'Neill, Meaghan P.
dc.contributor.authorSumner, Seirian
dc.contributor.authorPuiu, Daniela
dc.contributor.authorQu, Jiaxin
dc.contributor.authorSalzberg, Steven L.
dc.contributor.authorScherer, Steven E.
dc.contributor.authorMuzny, Donna M.
dc.contributor.authorRichards, Stephen
dc.contributor.authorRobinson, Gene E.
dc.contributor.authorGibbs, Richard A.
dc.contributor.authorSchmid-Hempel, Paul
dc.contributor.authorWorley, Kim C.
dc.contributor.otherIllinois State University
dc.contributor.otherSwiss Federal Institutes of Technology Domain
dc.contributor.otherETH Zurich
dc.contributor.otherUniversity of North Carolina
dc.contributor.otherEast Carolina University
dc.contributor.otherHebrew University of Jerusalem
dc.contributor.otherGhent University
dc.contributor.otherUniversity of Otago
dc.contributor.otherUniversity of Missouri Columbia
dc.contributor.otherGeorgetown University
dc.contributor.otherArizona State University
dc.contributor.otherArizona State University-Tempe
dc.contributor.otherUniversity of Copenhagen
dc.contributor.otherUniversity Hohenheim
dc.contributor.otherUniversity of Alabama Tuscaloosa
dc.contributor.otherUniversity of Illinois Urbana-Champaign
dc.contributor.otherMartin Luther University Halle Wittenberg
dc.contributor.otherUniversity of Geneva
dc.contributor.otherSwiss Institute of Bioinformatics
dc.contributor.otherMassachusetts Institute of Technology (MIT)
dc.contributor.otherHarvard University
dc.contributor.otherBroad Institute
dc.contributor.otherUniversity of Munster
dc.contributor.otherBarcelona Institute of Science & Technology
dc.contributor.otherPompeu Fabra University
dc.contributor.otherCentre de Regulacio Genomica (CRG)
dc.contributor.otherErnst Moritz Arndt Universitat Greifswald
dc.contributor.otherUniversity of California Berkeley
dc.contributor.otherUnited States Department of Energy (DOE)
dc.contributor.otherLawrence Berkeley National Laboratory
dc.contributor.otherNational Institutes of Health (NIH) - USA
dc.contributor.otherNIH National Library of Medicine (NLM)
dc.contributor.otherUniversity of East Anglia
dc.contributor.otherHeinrich Heine University Dusseldorf
dc.contributor.otherUniversity of Cologne
dc.contributor.otherUniversidade de Sao Paulo
dc.contributor.otherUniversity of Edinburgh
dc.contributor.otherUniversity of London
dc.contributor.otherRoyal Holloway University London
dc.contributor.otherUniversity of Bristol
dc.contributor.otherCommonwealth Scientific & Industrial Research Organisation (CSIRO)
dc.contributor.otherTrinity College Dublin
dc.contributor.otherZoological Society of London
dc.contributor.otherUnited States Department of Agriculture (USDA)
dc.contributor.otherNorth Carolina State University
dc.contributor.otherKyoto University
dc.contributor.otherInstituto Federal de Sao Paulo (IFSP)
dc.contributor.otherOhio State University
dc.contributor.otherOxford Brookes University
dc.contributor.otherUniversity of Southampton
dc.contributor.otherUniversity of Leicester
dc.contributor.otherUniversidade Federal de Sao Carlos
dc.contributor.otherUniversidade Estadual Paulista
dc.contributor.otherUniversity of North Carolina Greensboro
dc.contributor.otherNational Centre of Scientific Research "Demokritos"
dc.contributor.otherUniversity of Munich
dc.contributor.otherBaylor College of Medicine
dc.contributor.otherUTMD Anderson Cancer Center
dc.contributor.otherUniversity of Chicago
dc.contributor.otherQueen Mary University London
dc.contributor.otherGuangzhou University
dc.contributor.otherJohns Hopkins University
dc.date.accessioned2023-09-28T19:11:50Z
dc.date.available2023-09-28T19:11:50Z
dc.date.issued2015
dc.description.abstractBackground: The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. Bumblebees are also invaluable natural and agricultural pollinators, and there is widespread concern over recent population declines in some species. High-quality genomic data will inform key aspects of bumblebee biology, including susceptibility to implicated population viability threats. Results: We report the high quality draft genome sequences of Bombus terrestris and Bombus impatiens, two ecologically dominant bumblebees and widely utilized study species. Comparing these new genomes to those of the highly eusocial honeybee Apis mellifera and other Hymenoptera, we identify deeply conserved similarities, as well as novelties key to the biology of these organisms. Some honeybee genome features thought to underpin advanced eusociality are also present in bumblebees, indicating an earlier evolution in the bee lineage. Xenobiotic detoxification and immune genes are similarly depauperate in bumblebees and honeybees, and multiple categories of genes linked to social organization, including development and behavior, show high conservation. Key differences identified include a bias in bumblebee chemoreception towards gustation from olfaction, and striking differences in microRNAs, potentially responsible for gene regulation underlying social and other traits. Conclusions: These two bumblebee genomes provide a foundation for post-genomic research on these key pollinators and insect societies. Overall, gene repertoires suggest that the route to advanced eusociality in bees was mediated by many small changes in many genes and processes, and not by notable expansion or depauperation.en_US
dc.format.mediumelectronic
dc.format.mimetypeapplication/pdf
dc.identifier.citationSadd, B. M., Barribeau, S. M., Bloch, G., de Graaf, D. C., Dearden, P., Elsik, C. G., Gadau, J., Grimmelikhuijzen, C. J., Hasselmann, M., Lozier, J. D., Robertson, H. M., Smagghe, G., Stolle, E., Van Vaerenbergh, M., Waterhouse, R. M., Bornberg-Bauer, E., Klasberg, S., Bennett, A. K., Câmara, F., … Worley, K. C. (2015). The genomes of two key bumblebee species with primitive eusocial organization. In Genome Biology (Vol. 16, Issue 1). Springer Science and Business Media LLC. https://doi.org/10.1186/s13059-015-0623-3
dc.identifier.doi10.1186/s13059-015-0623-3
dc.identifier.orcidhttps://orcid.org/0000-0002-9764-2581
dc.identifier.orcidhttps://orcid.org/0000-0001-7790-9675
dc.identifier.orcidhttps://orcid.org/0000-0003-4199-9052
dc.identifier.orcidhttps://orcid.org/0000-0001-5370-4229
dc.identifier.orcidhttps://orcid.org/0000-0003-1624-4926
dc.identifier.orcidhttps://orcid.org/0000-0001-8324-7874
dc.identifier.orcidhttps://orcid.org/0000-0001-8153-1732
dc.identifier.orcidhttps://orcid.org/0000-0002-8859-7432
dc.identifier.orcidhttps://orcid.org/0000-0002-7759-0139
dc.identifier.orcidhttps://orcid.org/0000-0003-0791-887X
dc.identifier.orcidhttps://orcid.org/0000-0001-8334-3313
dc.identifier.orcidhttps://orcid.org/0000-0002-3162-4890
dc.identifier.orcidhttps://orcid.org/0000-0001-5850-340X
dc.identifier.orcidhttps://orcid.org/0000-0002-9425-8103
dc.identifier.orcidhttps://orcid.org/0000-0002-5619-6378
dc.identifier.orcidhttps://orcid.org/0000-0002-2431-0180
dc.identifier.orcidhttps://orcid.org/0000-0001-7638-4061
dc.identifier.orcidhttps://orcid.org/0000-0003-4354-9952
dc.identifier.orcidhttps://orcid.org/0000-0002-5178-1498
dc.identifier.orcidhttps://orcid.org/0000-0001-7062-5936
dc.identifier.orcidhttps://orcid.org/0000-0002-5738-4477
dc.identifier.orcidhttps://orcid.org/0000-0002-4248-7713
dc.identifier.orcidhttps://orcid.org/0000-0002-8859-7432
dc.identifier.orcidhttps://orcid.org/0000-0002-7411-4161
dc.identifier.orcidhttps://orcid.org/0000-0001-7981-8427
dc.identifier.orcidhttps://orcid.org/0000-0001-7981-8427
dc.identifier.orcidhttps://orcid.org/0000-0002-8603-6332
dc.identifier.orcidhttps://orcid.org/0000-0002-9619-3809
dc.identifier.orcidhttps://orcid.org/0000-0002-3675-3499
dc.identifier.orcidhttps://orcid.org/0000-0003-2861-949X
dc.identifier.orcidhttps://orcid.org/0000-0002-1971-5466
dc.identifier.orcidhttps://orcid.org/0000-0002-8936-0381
dc.identifier.orcidhttps://orcid.org/0000-0002-9764-2581
dc.identifier.orcidhttps://orcid.org/0000-0001-5563-2345
dc.identifier.orcidhttps://orcid.org/0000-0002-9619-3809
dc.identifier.orcidhttps://orcid.org/0000-0003-3305-4024
dc.identifier.orcidhttps://orcid.org/0000-0002-1826-3576
dc.identifier.orcidhttps://orcid.org/0000-0002-0036-4651
dc.identifier.orcidhttps://orcid.org/0000-0002-0717-9432
dc.identifier.orcidhttps://orcid.org/0000-0002-4737-0936
dc.identifier.orcidhttps://orcid.org/0000-0001-6643-0562
dc.identifier.orcidhttps://orcid.org/0000-0002-3675-3499
dc.identifier.orcidhttps://orcid.org/0000-0002-7769-3058
dc.identifier.orcidhttps://orcid.org/0000-0001-5370-4229
dc.identifier.orcidhttps://orcid.org/0000-0003-0213-2018
dc.identifier.orcidhttps://orcid.org/0000-0001-6696-840X
dc.identifier.orcidhttps://orcid.org/0000-0003-1492-5429
dc.identifier.orcidhttps://orcid.org/0000-0002-7835-0890
dc.identifier.orcidhttps://orcid.org/0000-0003-2363-6178
dc.identifier.orcidhttps://orcid.org/0000-0001-8959-5466
dc.identifier.orcidhttps://orcid.org/0000-0001-6486-2046
dc.identifier.orcidhttps://orcid.org/0000-0001-8619-8158
dc.identifier.orcidhttps://orcid.org/0000-0003-0352-6289
dc.identifier.orcidhttps://orcid.org/0000-0002-1088-5282
dc.identifier.orcidhttps://orcid.org/0000-0003-0857-4298
dc.identifier.orcidhttps://orcid.org/0000-0002-2385-2973
dc.identifier.orcidhttps://orcid.org/0000-0002-1399-5188
dc.identifier.orcidhttps://orcid.org/0000-0001-8817-0781
dc.identifier.orcidhttps://orcid.org/0000-0003-4303-6364
dc.identifier.orcidhttps://orcid.org/0000-0002-2799-1217
dc.identifier.orcidhttps://orcid.org/0000-0002-0547-8228
dc.identifier.orcidhttps://orcid.org/0000-0002-5799-8639
dc.identifier.orcidhttps://orcid.org/0000-0003-3759-2145
dc.identifier.orcidhttps://orcid.org/0000-0003-3725-5640
dc.identifier.orcidhttps://orcid.org/0000-0002-1841-504X
dc.identifier.orcidhttps://orcid.org/0000-0003-3199-5277
dc.identifier.orcidhttps://orcid.org/0000-0001-5092-674X
dc.identifier.orcidhttps://orcid.org/0000-0003-1411-2313
dc.identifier.orcidhttps://orcid.org/0000-0002-0747-8539
dc.identifier.orcidhttps://orcid.org/0000-0003-1027-4075
dc.identifier.orcidhttps://orcid.org/0000-0003-3398-8943
dc.identifier.orcidhttps://orcid.org/0000-0001-7433-2444
dc.identifier.orcidhttps://orcid.org/0000-0003-3136-5144
dc.identifier.orcidhttps://orcid.org/0000-0002-0282-1000
dc.identifier.orcidhttps://orcid.org/0000-0002-3680-3767
dc.identifier.urihttps://ir.ua.edu/handle/123456789/11033
dc.languageEnglish
dc.language.isoen_US
dc.publisherBMC
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectSEX-DETERMINATION PATHWAY
dc.subjectMULTIPLE SEQUENCE ALIGNMENT
dc.subjectBOMBUS-TERRESTRIS LINNAEUS
dc.subjectHONEY-BEE
dc.subjectAPIS-MELLIFERA
dc.subjectDRAFT GENOME
dc.subjectCHEMORECEPTOR SUPERFAMILY
dc.subjectDROSOPHILA-MELANOGASTER
dc.subjectNEUROHORMONE GPCRS
dc.subjectCOMBINED PESTICIDE
dc.subjectBiotechnology & Applied Microbiology
dc.subjectGenetics & Heredity
dc.titleThe genomes of two key bumblebee species with primitive eusocial organizationen_US
dc.typeArticle
dc.typetext
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
PMC4414376-13059_2015_Article_623.pdf
Size:
2.46 MB
Format:
Adobe Portable Document Format