UA cloudflare authentication

 

Supramolecular Carotenoid Complexes of Enhanced Solubility and Stability-The Way of Bioavailability Improvement

Simple item page
dc.contributor.authorFocsan, A. Ligia
dc.contributor.authorPolyakov, Nikolay E.
dc.contributor.authorKispert, Lowell D.
dc.contributor.otherValdosta State University
dc.contributor.otherVoevodsky Institute of Chemical Kinetics & Combustion SB RAS
dc.contributor.otherInstitute of Solid State Chemistry & Mechanochemistry, Siberian Branch of the Russian Academy of Sciences
dc.contributor.otherUniversity of Alabama Tuscaloosa
dc.date.accessioned2023-09-28T19:17:56Z
dc.date.available2023-09-28T19:17:56Z
dc.date.issued2019
dc.description.abstractCarotenoids are natural dyes and antioxidants widely used in food processing and in therapeutic formulations. However, their practical application is restricted by their high sensitivity to external factors such as heat, light, oxygen, metal ions and processing conditions, as well as by extremely low water solubility. Various approaches have been developed to overcome these problems. In particular, it was demonstrated that application of supramolecular complexes of "host-guest" type with water-soluble nanoparticles allows minimizing the abovementioned disadvantages. From this point of view, nanoencapsulation of carotenoids is an effective strategy to improve their stability during storage and food processing. Also, nanoencapsulation enhances bioavailability of carotenoids via modulating their release kinetics from the delivery system, influencing the solubility and absorption. In the present paper, we present the state of the art of carotenoid nanoencapsulation and summarize the data obtained during last five years on preparation, analysis and reactivity of carotenoids encapsulated into various nanoparticles. The possible mechanisms of carotenoids bioavailability enhancement by multifunctional delivery systems are also discussed.en_US
dc.format.mediumelectronic
dc.format.mimetypeapplication/pdf
dc.identifier.citationFocsan, Polyakov, & Kispert. (2019). Supramolecular Carotenoid Complexes of Enhanced Solubility and Stability—The Way of Bioavailability Improvement. In Molecules (Vol. 24, Issue 21, p. 3947). MDPI AG. https://doi.org/10.3390/molecules24213947
dc.identifier.doi10.3390/molecules24213947
dc.identifier.orcidhttps://orcid.org/0000-0002-3666-7750
dc.identifier.urihttps://ir.ua.edu/handle/123456789/11262
dc.languageEnglish
dc.language.isoen_US
dc.publisherMDPI
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectcarotenoids
dc.subjectinclusion complexes
dc.subjectdelivery systems
dc.subjectnanoemulsions
dc.subjectnanoliposomes
dc.subjectbiopolymeric nanoparticles
dc.subjectwater solubility
dc.subjectoxidation stability
dc.subjectphotostability
dc.subjectbioavailability
dc.subjectNANOSTRUCTURED LIPID CARRIERS
dc.subjectWATER-SOLUBLE COMPLEXES
dc.subjectGLYCYRRHIZIC ACID
dc.subjectBETA-CAROTENE
dc.subjectDELIVERY-SYSTEMS
dc.subjectCYCLOMALTOOLIGOSACCHARIDES CYCLODEXTRINS
dc.subjectPHYSICOCHEMICAL CHARACTERIZATION
dc.subjectNONCOVALENT ASSOCIATIONS
dc.subjectTRANSDERMAL DELIVERY
dc.subjectANTIOXIDANT ACTIVITY
dc.subjectBiochemistry & Molecular Biology
dc.subjectChemistry, Multidisciplinary
dc.titleSupramolecular Carotenoid Complexes of Enhanced Solubility and Stability-The Way of Bioavailability Improvementen_US
dc.typeReview
dc.typetext

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
PMC6864715-molecules-24-03947.pdf
Size:
1.76 MB
Format:
Adobe Portable Document Format
Download

Collections

Research and Publications - Department of Chemistry & Biochemistry