Continuous drug infusion for diabetes therapy: A closed-loop control system design

dc.contributor.authorChen, Jiming
dc.contributor.authorCao, Kejie
dc.contributor.authorSun, Youxian
dc.contributor.authorXiao, Yang
dc.contributor.authorSu, Xu (Kevin)
dc.contributor.otherZhejiang University
dc.contributor.otherUniversity of Alabama Tuscaloosa
dc.contributor.otherUniversity of Texas System
dc.contributor.otherUniversity of Texas at San Antonio (UTSA)
dc.date.accessioned2021-06-29T20:37:54Z
dc.date.available2021-06-29T20:37:54Z
dc.date.issued2007
dc.description.abstractWhile a typical way for diabetes therapy is discrete insulin infusion based on long-time interval measurement, in this paper, we design a closed-loop control system for continuous drug infusion to improve the traditional discrete methods and make diabetes therapy automatic in practice. By exploring the accumulative function of drug to insulin, a continuous injection model is proposed. Based on this model, proportional-integral-derivative (PID) and fuzzy logic controllers are designed to tackle a control problem of the resulting highly nonlinear plant. Even with serious disturbance of glucose, such as nutrition absorption at meal time, the proposed scheme can perform well in simulation experiments. Copyright (c) 2008.Jiming Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.format.mimetypeapplication/pdf
dc.identifier.citationChen, J., Cao, K., Sun, Y., Xiao, Y., Su, X. (2007): Continuous Drug Infusion for Diabetes Therapy: A Closed-Loop Control System Design. EURASIP Journal on Wireless Communications and Networking. Volume 2008
dc.identifier.doi10.1155/2008/495185
dc.identifier.orcidhttps://orcid.org/0000-0001-8549-6794
dc.identifier.orcidhttps://orcid.org/0000-0003-3155-3145
dc.identifier.urihttp://ir.ua.edu/handle/123456789/7817
dc.languageEnglish
dc.language.isoen_US
dc.publisherSpringer
dc.rights.urihttps://creativecommons.org/licenses/by/2.0/
dc.subjectGLUCOSE REGULATION
dc.subjectALGORITHM
dc.subjectSENSOR
dc.subjectMODEL
dc.subjectEngineering, Electrical & Electronic
dc.subjectTelecommunications
dc.subjectEngineering
dc.titleContinuous drug infusion for diabetes therapy: A closed-loop control system designen_US
dc.typetext
dc.typeArticle
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