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Does Chronic Cannabis Use Impact Risky Decision-Making: An Examination of fMRI Activation and Effective Connectivity?

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dc.contributor.authorRaymond, David R.
dc.contributor.authorPaneto, Adrian
dc.contributor.authorYoder, Karmen K.
dc.contributor.authorO'Donnell, Brian F.
dc.contributor.authorBrown, Joshua W.
dc.contributor.authorHetrick, William P.
dc.contributor.authorNewman, Sharlene D.
dc.contributor.otherIndiana University System
dc.contributor.otherIndiana University Bloomington
dc.contributor.otherIndiana University-Purdue University Indianapolis
dc.contributor.otherUniversity of Alabama Tuscaloosa
dc.date.accessioned2021-07-28T14:22:30Z
dc.date.available2021-07-28T14:22:30Z
dc.date.issued2020
dc.description.abstractWith the increase in use of cannabis and its shifting legal status in the United States, cannabis use has become an important research focus. While studies of other drug populations have shown marked increases in risky decision-making, the literature on cannabis users is not as clear. The current study examined the performance of 17 cannabis users and 14 non-users on the Balloon Analog Risk Task (BART) using behavioral, fMRI and effective connectivity methods. Significant attenuation was found in a functional pathway projecting from the dorsal anterior cingulate cortex (dACC) to the nucleus accumbens (NAc) in cannabis users compared to non-using controls as well as decreases in risk-taking behaviors. These findings suggest that cannabis users may process and evaluate risks and rewards differently than non-users.en_US
dc.format.mimetypeapplication/pdf
dc.identifier.citationRaymond, D., Paneto, A., Yoder, K., O’Donnell, B., Brown, J., Hetrick, W., Newman, S. (2020): Does Chronic Cannabis UseImpact Risky Decision-Making: An Examination of fMRI Activation and Effective Connectivity. Frontiers in Psychiatry. Volume 11.
dc.identifier.doi10.3389/fpsyt.2020.599256
dc.identifier.orcidhttps://orcid.org/0000-0001-8795-4568
dc.identifier.urihttp://ir.ua.edu/handle/123456789/7984
dc.languageEnglish
dc.language.isoen_US
dc.publisherFrontiers Media
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectcannabis
dc.subjectdecision-making
dc.subjecteffective connectivity
dc.subjectfMRI
dc.subjectreward
dc.subjectrisk
dc.subjectNUCLEUS-ACCUMBENS CORE
dc.subjectFUNCTIONAL CONNECTIVITY
dc.subjectRESPONSE-INHIBITION
dc.subjectDRUG-ADDICTION
dc.subjectTASK BART
dc.subjectSCHIZOPHRENIA
dc.subjectPERFORMANCE
dc.subjectPSYCHOSIS
dc.subjectBEHAVIOR
dc.subjectCORTEX
dc.subjectPsychiatry
dc.titleDoes Chronic Cannabis Use Impact Risky Decision-Making: An Examination of fMRI Activation and Effective Connectivity?en_US
dc.typetext
dc.typeArticle

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