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Cost and effectiveness of one session treatment (OST) for children and young people with specific phobias compared to multi-session cognitive behavioural therapy (CBT): results from a randomised controlled trial

dc.contributor.authorWang, Han-, I
dc.contributor.authorWright, Barry
dc.contributor.authorTindall, Lucy
dc.contributor.authorCooper, Cindy
dc.contributor.authorBiggs, Katie
dc.contributor.authorLee, Ellen
dc.contributor.authorTeare, M. Dawn
dc.contributor.authorGega, Lina
dc.contributor.authorScott, Alexander J.
dc.contributor.authorHayward, Emily
dc.contributor.authorSolaiman, Kiera
dc.contributor.authorDavis, Thompson
dc.contributor.authorMcMillan, Dean
dc.contributor.authorGilbody, Simon
dc.contributor.authorParrott, Steve
dc.contributor.otherUniversity of York - UK
dc.contributor.otherUniversity of Sheffield
dc.contributor.otherNewcastle University - UK
dc.contributor.otherUniversity of Hull
dc.contributor.otherKeele University
dc.contributor.otherLouisiana State University
dc.contributor.otherUniversity of Alabama Tuscaloosa
dc.date.accessioned2023-09-28T20:40:15Z
dc.date.available2023-09-28T20:40:15Z
dc.date.issued2022
dc.description.abstractBackground In the UK, around 93,000 (0.8%) children and young people (CYP) are experiencing specific phobias that have a substantial impact on daily life. The current gold-standard treatment-multi-session cognitive behavioural therapy (CBT) - is effective at reducing specific phobia severity; however, CBT is time consuming, requires specialist CBT therapists, and is often at great cost and limited availability. A briefer variant of CBT called one session treatment (OST) has been found to offer similar clinical effectiveness for specific phobia as multi-session CBT. The aim of this study was to assess the cost-effectiveness of OST compared to multi-session CBT for CYP with specific phobias through the Alleviating Specific Phobias Experienced by Children Trial (ASPECT), a two-arm, pragmatic, multi-centre, non-inferiority randomised controlled trial. Methods CYP aged seven to 16 years with specific phobias were recruited nationally via Health and Social Care pathways, remotely randomised to the intervention group (OST) or the control group (CBT-based therapies) and analysed (n = 267). Resource use based on NHS and personal social services perspective and quality adjusted life years (QALYs) measured by EQ-5D-Y were collected at baseline and at six-month follow-up. Incremental cost-effectiveness ratio (ICER) was calculated, and non-parametric bootstrapping was conducted to capture the uncertainty around the ICER estimates. The results were presented on a cost-effectiveness acceptability curve (CEAC). A set of sensitivity analyses (including taking a societal perspective) were conducted to assess the robustness of the primary findings. Results After adjustment and bootstrapping, on average CYP in the OST group incurred less costs (incremental cost was -302.96 pound (95% CI -598.86 pound to -28.61)) pound and maintained similar improvement in QALYs (QALYs gained 0.002 (95% CI - 0.004 to 0.008)). The CEAC shows that the probability of OST being cost-effective was over 95% across all the WTP thresholds. Results of a set of sensitivity analyses were consistent with the primary outcomes. Conclusion Compared to CBT, OST produced a reduction in costs and maintained similar improvement in QALYs. Results from both primary and sensitivity analyses suggested that OST was highly likely to be cost saving.en_US
dc.format.mediumelectronic
dc.format.mimetypeapplication/pdf
dc.identifier.citationWang, H.-I., Wright, B., Tindall, L., Cooper, C., Biggs, K., Lee, E., Teare, M. D., Gega, L., Scott, A. J., Hayward, E., Solaiman, K., Davis, T., McMillan, D., Gilbody, S., & Parrott, S. (2022). Cost and effectiveness of one session treatment (OST) for children and young people with specific phobias compared to multi-session cognitive behavioural therapy (CBT): results from a randomised controlled trial. In BMC Psychiatry (Vol. 22, Issue 1). Springer Science and Business Media LLC. https://doi.org/10.1186/s12888-022-04192-8
dc.identifier.doi10.1186/s12888-022-04192-8
dc.identifier.orcidhttps://orcid.org/0000-0002-8236-6983
dc.identifier.orcidhttps://orcid.org/0000-0002-2995-5447
dc.identifier.orcidhttps://orcid.org/0000-0003-4529-7410
dc.identifier.orcidhttps://orcid.org/0000-0002-0165-1150
dc.identifier.orcidhttps://orcid.org/0000-0003-4468-7417
dc.identifier.urihttps://ir.ua.edu/handle/123456789/11762
dc.languageEnglish
dc.language.isoen_US
dc.publisherBMC
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCost-effectiveness
dc.subjectChild
dc.subjectAdolescent
dc.subjectPhobic disorders
dc.subjectMental health services
dc.subjectCost
dc.subjectEQ-5D-Y
dc.subjectOne session treatment
dc.subjectCognitive behavioural therapy
dc.subjectANXIETY DISORDERS
dc.subjectHEALTH
dc.subjectYOUTH
dc.subjectPsychiatry
dc.titleCost and effectiveness of one session treatment (OST) for children and young people with specific phobias compared to multi-session cognitive behavioural therapy (CBT): results from a randomised controlled trialen_US
dc.typeArticle
dc.typetext

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