Positive mental well-being and immune transcriptional profiles in highly involved videogame players

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dc.contributor.authorSnodgrass, Jeffrey G.
dc.contributor.authorLacy, Michael G.
dc.contributor.authorDengah, H. J. Francois, II
dc.contributor.authorPolzer, Evan R.
dc.contributor.authorElse, Robert J.
dc.contributor.authorArevalo, Jesusa M. G.
dc.contributor.authorCole, Steven W.
dc.contributor.otherColorado State University
dc.contributor.otherUtah State University
dc.contributor.otherUniversity of Colorado Anschutz Medical Campus
dc.contributor.otherUniversity of Alabama Tuscaloosa
dc.contributor.otherUniversity of California Los Angeles
dc.contributor.otherUniversity of California Los Angeles Medical Center
dc.contributor.otherDavid Geffen School of Medicine at UCLA
dc.date.accessioned2023-09-29T12:45:11Z
dc.date.available2023-09-29T12:45:11Z
dc.date.issued2019
dc.description.abstractPrevious research has identified a link between experiencing life as meaningful and purposeful-what is referred to as "eudaimonia"-and reduced expression of a stress-induced gene profile known as the "conserved transcriptional response to adversity" (CTRA). In the current study, we examine whether similar links between eudaimonic well-being and CTRA reduction occur in a sample of 56 individuals with a particularly strong engagement with virtual worlds: avid online videogame players. Results consistently linked higher eudaimonic well-being, and more specifically the social well-being subdomain of eudaimonia, to lower levels of CTRA gene expression. That favorable psychobiological relationship between eudaimonia and CTRA appeared most strongly among individuals reporting high levels of positive psychosocial involvement with gaming. Findings are consistent with the hypothesis that committed social/recreational activity may help damp CTRA expression especially among persons who are already experiencing some kind of threshold of positive eudaimonic experience.en_US
dc.format.mediumelectronic
dc.format.mimetypeapplication/pdf
dc.identifier.citationSnodgrass, J. G., Lacy, M. G., Dengah, H. J. F., II, Polzer, E. R., Else, R. J., Arevalo, J. M. G., & Cole, S. W. (2019). Positive mental well-being and immune transcriptional profiles in highly involved videogame players. In Brain, Behavior, and Immunity (Vol. 82, pp. 84–92). Elsevier BV. https://doi.org/10.1016/j.bbi.2019.07.035
dc.identifier.doi10.1016/j.bbi.2019.07.035
dc.identifier.orcidhttps://orcid.org/0000-0003-0780-5154
dc.identifier.orcidhttps://orcid.org/0000-0003-3646-5160
dc.identifier.urihttps://ir.ua.edu/handle/123456789/12384
dc.languageEnglish
dc.language.isoen_US
dc.publisherElsevier
dc.subjectSocial genomics
dc.subjectOnline games
dc.subjectEudaimonia
dc.subjectWell-being
dc.subjectBiocultural anthropology
dc.subjectINFLAMMATORY GENE-EXPRESSION
dc.subjectINTERNET GAMING DISORDER
dc.subjectBREAST-CANCER SURVIVORS
dc.subjectDRIED BLOOD SPOTS
dc.subjectLEUKOCYTE TRANSCRIPTOME
dc.subjectREGULATORY IMPACT
dc.subjectMMO PLAY
dc.subjectSTRESS
dc.subjectDYNAMICS
dc.subjectCONSEQUENCES
dc.subjectImmunology
dc.subjectNeurosciences
dc.subjectPsychiatry
dc.titlePositive mental well-being and immune transcriptional profiles in highly involved videogame playersen_US
dc.typeArticle
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