Rationale for the tinnitus retraining therapy trial

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dc.contributor.authorTRTT Study Grp
dc.contributor.authorFormby, Craig
dc.contributor.authorScherer, Roberta
dc.contributor.otherUniversity of Alabama Tuscaloosa
dc.contributor.otherJohns Hopkins University
dc.contributor.otherJohns Hopkins Bloomberg School of Public Health
dc.date.accessioned2023-09-28T19:30:22Z
dc.date.available2023-09-28T19:30:22Z
dc.date.issued2013
dc.description.abstractThe Tinnitus Retraining Therapy Trial (TRTT) is a National Institutes of Health-sponsored, multi-centered, placebo-controlled, randomized trial evaluating the efficacy of tinnitus retraining therapy (TRT) and its component parts, directive counseling and sound therapy, as treatments for subjective debilitating tinnitus in the military. The TRTT will enroll 228 individuals at an allocation ratio of 1: 1: 1 to: (1) directive counseling and sound therapy using conventional sound generators; (2) directive counseling and placebo sound generators; or (3) standard of care as administered in the military. Study centers include a Study Chair's Office, a Data Coordinating Center, and six Military Clinical Centers with treatment and data collection standardized across all clinics. The primary outcome is change in Tinnitus Questionnaire (TQ) score assessed longitudinally at 3, 6, 12, and 18-month follow-up visits. Secondary outcomes include: Change in TQ sub-scales, Tinnitus Handicap Inventory, Tinnitus Functional Index, and TRT interview visual analog scale; audiometric and psychoacoustic measures; and change in quality of life. The TRTT will evaluate TRT efficacy by comparing TRT (directive counseling and conventional sound generators) with standard of care; directive counseling by comparing directive counseling plus placebo sound generators versus standard of care; and sound therapy by comparing conventional versus placebo sound generators. We hypothesize that full TRT will be more efficacious than standard of care, directive counseling and placebo sound generators more efficacious than standard of care, and conventional more efficacious than placebo sound generators in habituating the tinnitus awareness, annoyance, and impact on the study participant's life.en_US
dc.format.mediumelectronic
dc.format.mimetypeapplication/pdf
dc.identifier.citationFormby, C., & Scherer, R. (2013). Rationale for the tinnitus retraining therapy trial. In Noise and Health (Vol. 15, Issue 63, p. 134). Medknow. https://doi.org/10.4103/1463-1741.110299
dc.identifier.doi10.4103/1463-1741.110299
dc.identifier.orcidhttps://orcid.org/0000-0002-9468-5412
dc.identifier.urihttps://ir.ua.edu/handle/123456789/11337
dc.languageEnglish
dc.language.isoen_US
dc.publisherWolters Kluwer
dc.subjectRandomized controlled trials
dc.subjecttinnitus
dc.subjecttinnitus retraining therapy
dc.subjectNEUROPHYSIOLOGICAL APPROACH
dc.subjectADAPTIVE PLASTICITY
dc.subjectCLINICAL-TRIAL
dc.subjectPERCEPTION
dc.subjectOUTCOMES
dc.subjectAudiology & Speech-Language Pathology
dc.subjectPublic, Environmental & Occupational Health
dc.titleRationale for the tinnitus retraining therapy trialen_US
dc.typeArticle
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