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Browsing Theses and Dissertations - Department of Biological Sciences by Subject "Cellular biology"

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Characterization of the roles of phosholipase B1 and the cyclic-AMP (cAMP)-protein kinase A (PKA) pathway in nutritional and osmotic stress response in Schizosaccharomyces pombe

McInnis, Brittney (University of Alabama Libraries, 2012)

Physiological stress is a reality faced by all cells. Even though these stresses are often disruptive of normal cellular function, cells must adapt to the stressor or perish. This study utilizes the model organism ...
Exploring the role of torsina in ER stress and stress related diseases in C. elegans

Chen, Pan (University of Alabama Libraries, 2011)

Early-onset torsion dystonia (EOTD) is the most severe heritable form of dystonia, a human movement disorder that typically starts in childhood. A glutamic acid deletion (deltaE) in the DYT1 gene, encoding the torsinA ...
Functional analysis of neuroprotective genes using caenorhabditis elegans and mammalian models of Parkinson's disease

Harrington, Adam John (University of Alabama Libraries, 2011)

Dysfunction of the protein degradation machinery has emerged as a leading cellular defect associated with age-onset proteotoxicity in neurodegenerative diseases, including Parkinson's disease (PD). While the etiology of ...
Gene-by-environment stressor interactions integrate at the mitochondria to determine severity of detrimental proteostatic and cellular health-related phenotypes in C. elegans models of Parkinson’s disease

Martinez, Bryan A. (University of Alabama Libraries, 2017)

Parkinson’s disease (PD) associates with selective degeneration of midbrain dopaminergic neurons culminating in irreversible motor dysfunction such as gait instability and tremors. Despite the localized nature of toxicity, ...
The role of ubiquitination in the innate immune system in arabidopsis

Guo, Tingwei (University of Alabama Libraries, 2018)

My research using the model plant Arabidopsis thaliana is focused on unraveling the signal transduction pathways involved in elicitor-mediated plant defense, particularly defense pathways involved in resistance to fungal ...

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Browsing Theses and Dissertations - Department of Biological Sciences by Subject "Cellular biology"

Browsing Theses and Dissertations - Department of Biological Sciences by Subject "Cellular biology"

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