We study the collider signature of pseudo-Dirac heavy neutrinos in the inverse seesaw scenario, where the heavy neutrinos with mass at the electroweak scale can have sizable mixings with the Standard Model neutrinos, while providing the tiny light neutrino masses by the inverse seesaw mechanism. Based on a simple, concrete model realizing the inverse seesaw scenario, we fix the model parameters so as to reproduce the neutrino oscillation data and to satisfy other experimental constraints, assuming two typical flavor structures of the model and the different types of hierarchical light neutrino mass spectra. For completeness, we also consider a general parametrization for the model parameters by introducing an arbitrary orthogonal matrix and the nonzero Dirac and Majorana phases. We perform a parameter scan to identify an allowed parameter region which satisfies all experimental constraints. With the fixed parameters, we analyze the heavy neutrino signal at the LHC through trilepton final states with large missing energy and at the ILC through a single lepton plus dijet with large missing energy. We find that in some cases, the heavy neutrino signal can be observed with a large statistical significance via different flavor charged lepton final states.