Human canalization and female growth buffering with Drosophila as a model organism

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dc.contributor Pritzker, Sonya E.
dc.contributor Weaver, Lesley Jo
dc.contributor.advisor DeCaro, Jason A.
dc.contributor.advisor Reed, Laura K.
dc.contributor.author Spangler, Daryll Ross
dc.date.accessioned 2018-12-14T18:12:40Z
dc.date.available 2018-12-14T18:12:40Z
dc.date.issued 2018
dc.identifier.other u0015_0000001_0003151
dc.identifier.other Spangler_alatus_0004M_13594
dc.identifier.uri http://ir.ua.edu/handle/123456789/5283
dc.description Electronic Thesis or Dissertation
dc.description.abstract Child health is a central concern in populations experiencing economic, environmental, and nutritional stress. Adversity, however, does not affect individuals uniformly as preferential child investment and underlying biological processes may lead to instances of differential growth outcomes among boys and girls. The causes of such differences may be misinterpreted when examining health and nutrition survey data and are deserving of inspection. This research utilizes an evolutionary female canalization model to broadly contextualize observed instances of sex-specific growth outcomes. The objectives of this research are to: (1) investigate sex-specific differences in growth and development; (2) address contributing cultural factors of the target population; (3) create a biological framework for understanding female canalization; and (4) create a robust understanding of sex-specific growth outcomes that can be used to interpret health and nutrition survey data. To complete these objectives, this research uses the Cebu Longitudinal Health and Nutrition Survey of the Philippines as a database for analysis. Drosophila melanogaster was employed as a model organism to investigate female canalization as an ancestral biological and evolutionary mechanism present in both Drosophila and humans. Human results indicate that girls are less sensitive to adverse environmental conditions and show more stable patterns of growth and development than boys. Drosophila results suggest there to be significant sex, diet, and genotype interactions that contribute to differential male and female phenotypic outcomes. These results show there are shared, sex-specific developmental characteristics between humans and Drosophila and that an understanding of contributing factors is crucial to future interpretations of health and nutrition survey data.
dc.format.extent 87 p.
dc.format.medium electronic
dc.format.mimetype application/pdf
dc.language English
dc.language.iso en_US
dc.publisher University of Alabama Libraries
dc.relation.ispartof The University of Alabama Electronic Theses and Dissertations
dc.relation.ispartof The University of Alabama Libraries Digital Collections
dc.relation.hasversion born digital
dc.rights All rights reserved by the author unless otherwise indicated.
dc.subject.other Cultural anthropology
dc.subject.other Biology
dc.title Human canalization and female growth buffering with Drosophila as a model organism
dc.type thesis
dc.type text
etdms.degree.department University of Alabama. Department of Anthropology
etdms.degree.discipline Anthropology
etdms.degree.grantor The University of Alabama
etdms.degree.level master's
etdms.degree.name M.A.


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