Research and Publications - Department of Family, Internal, and Rural Medicine

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    Malakoplakia of the Kidney Transplant
    (Elsevier, 2023) Triozzi, Jefferson L.; V. Rodriguez, Joshua; Velagapudi, Ramya; Fallahzadeh, Mohammad Kazem; Binari, Laura A.; Paueksakon, Paisit; Fogo, Agnes B.; Concepcion, Beatrice P.; Vanderbilt University; University of Alabama Tuscaloosa; University of Cincinnati; Emory University
    Malakoplakia is a rare granulomatous disease associated with infection.1 Malakoplakia most often involves the bladder, although it can affect any organ, including the native or transplanted kidney.2,3 Indeed, solid organ transplant recipients and other immunocompromised individuals are at increased risk of malakoplakia. This case report and systematic re-view of the literature raises important considerations related to malakoplakia of the kidney transplant.
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    Factors Associated with Likelihood to Undergo Cosmetic Surgical Procedures Among Young Adults in the United States: A Narrative Review
    (Dove Medical Press, 2022) Pearlman, Ross L.; Wilkerson, Amanda H.; Cobb, Emily K.; Morrissette, Summer; Lawson, Frances G.; Mockbee, Chelsea S.; Humphries, Laura S.; Ward, Kimberley H. M.; Nahar, Vinayak K.; University of Mississippi Medical Center; University of Mississippi; University of Alabama Tuscaloosa
    Introduction/Goals: Over the past decade, cosmetic surgical procedures have become increasingly popular. This trend has been driven by procedural innovations as well as access to Internet and social media. Consequently, patients have been seeking cosmetic surgical procedures at younger ages. In this narrative review, studies assessing attitudes towards cosmetic surgical procedures among college-aged young adults were evaluated. Methods: A search identified 20 studies published from 2002 to 2021 that focused on cosmetic surgical procedures among young adults. Each study used survey-based data to determine attitudes, acceptance, interests, perceptions, and beliefs about cosmetic surgical procedures among college-aged students in the United States. Results: The proportion of college-aged participants who had undergone cosmetic surgical procedures ranged from 1.3% to 6.4% with surveys reporting that between 21 and 43% were interested in procedures in the future. In general, young women were more likely to express interest in cosmetic surgical procedures than young men. Studies consistently demonstrated an inverse relationship between body satisfaction and use of aesthetic procedures among this patient population. Other factors associated with acceptance and approval of cosmetic surgical procedures included importance of appearance to self-worth, concern with social standing and attractiveness, investment in appearance, media influence on body image, and positive attitudes towards celebrities. Exposure to cosmetic surgery advertising was correlated with increased approval of cosmetic surgical procedures, especially the perception that advertising influences "others" more than survey respondents themselves. Conclusion: Interest in cosmetic surgical procedures continues to grow among young adults in the United States. In the future, this cohort is likely to become an increasingly important demographic to target for education, advertising, and research regarding cosmetic surgical procedures.
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    Skin Rash in a Stage 4 CKD Patient Treated for Hyperkalemia
    (American Society of Nephrology, 2021) Boge, Hanna; Almehmi, Sloan; Almehmi, Ammar; University of Alabama Tuscaloosa; University of Alabama Birmingham
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    The association of wound factors and symptoms of fatigue and pain with wound healing in chronic venous leg ulcers
    (Wiley, 2023) Kim, Junglyun; Stechmiller, Joyce; Weaver, Michael; Gibson, Daniel J.; Horgas, Ann; Kelly, Debra L.; Lyon, Debra E.; Chungnam National University; University of Florida; University of Alabama Tuscaloosa
    The purpose of this study was: (1) to characterise the association of wound area, wound exudate C-reactive protein (CRP), broad-spectrum matrix metalloprotease protein (MMPs), and symptoms of fatigue and pain in individuals with chronic venous leg ulcers (CVLUs) over time and (2) to identify factors associated with the wound healing trajectory in CVLUs. Seventy four participants with CVLU who received weekly sharp debridement were recruited from a wound care clinic during the 8-week study period. To examine associations among wound CRP, MMPs, pain, fatigue, and wound healing trajectory over time, we calculated Bayes factors (BF) based on a linear mixed model. The mean age of participants was 71.8 (SD = 9.8) and the mean wound area was 2278 mm(2) (SD = 7085 mm(2)) at baseline. Higher fatigue was strongly associated with higher MMPs (BF = 9, 95% HDI: [-.05, .43]), lower CRP (BF = 11, 95% HDI: [-.02, .002]), and large areas of wound (BF = 20, 95% HDI: [-.001, .01]). Higher CRP and MMPs activity in wound exudate and higher fatigue were associated with a larger wound area. To facilitate wound healing, clinicians need to utilise the multifactorial approach, which includes wound treatment and management of symptoms such as pain and fatigue, because of the molecular and psycho-behavioural factors involved in wound healing.
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    Medical Education and Medical Care in Alabama: Some Inadequacies, Some Solutions
    (1983) Willard, William R.; University of Alabama Tuscaloosa
    Appraisal of medical education and the problems of rural health in Alabama with some suggestions for improvement published in 1983 by the University of Alabama College of Community Health Sciences